Scadenza: 31 August 2021

Topic:

The MTFMT gene (Mitochondrial methionyl-tRNA formyltransferase) is an actor in the initiation of the translation and elongation of mitochondrial proteins. Mutations in the MTFMT gene have been associated with Leigh syndrome and several pathologies related to the mitochondrial respiratory chain. Leigh syndrome or subacute necrotizing encephalomyopathy is a progressive neurological disease with a very severe prognosis. There is currently no specific treatment. This call for projects aims to develop research on Leigh syndrome and the MTFMT gene. All biomedical disciplines are eligible.

Ente finanziatore:

Fondation Maladies Rares (Foundation For Rare Diseases - FFRD)
Association contre les Maladies Mitochondriales (AMMi)

Duration of the project: 18 months

Who can participate:

The principal investigator ("lead applicant") must be a researcher, belonging to a research organization . It is expected that the lead applicant will be statutory and in a permanent position. Otherwise, the lead applicant will have to provide proof of an employment contract with the research organization managing the allocated funds. The employment contract will have to run for the duration of the research project.

Partnership: Not Mandatory

Status:

Closed

Quota finanziabile:

10.000 €

Topic:
The MTFMT gene (Mitochondrial methionyl-tRNA formyltransferase) is an actor in the initiation of the translation and elongation of mitochondrial proteins. Mutations in the MTFMT gene have been associated with Leigh syndrome and several pathologies related to the mitochondrial respiratory chain. Leigh syndrome or subacute necrotizing encephalomyopathy is a progressive neurological disease with a very severe prognosis. There is currently no specific treatment. This call for projects aims to develop research on Leigh syndrome and the MTFMT gene. All biomedical disciplines are eligible.

Who can participate:
The principal investigator ("lead applicant") must be a researcher, belonging to a research organization . It is expected that the lead applicant will be statutory and in a permanent position. Otherwise, the lead applicant will have to provide proof of an employment contract with the research organization managing the allocated funds. The employment contract will have to run for the duration of the research project.

Programme:

Consortium: Not required

Status: Open

Total budget:

Funding rate:
10.000 €



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